Darren K McGuire Selected Research

Diabetic Ketoacidosis (Ketoacidosis, Diabetic)

1/2021	Effect of Dapagliflozin on Cardiovascular Outcomes According to Baseline Kidney Function and Albuminuria Status in Patients With Type 2 Diabetes: A Prespecified Secondary Analysis of a Randomized Clinical Trial.
1/2021	Sotagliflozin in Patients with Diabetes and Chronic Kidney Disease.
11/2020	Diabetic Ketoacidosis and Related Events With Sotagliflozin Added to Insulin in Adults With Type 1 Diabetes: A Pooled Analysis of the inTandem 1 and 2 Studies.
1/2020	Efficacy and Safety of Dapagliflozin in the Elderly: Analysis From the DECLARE-TIMI 58 Study.
1/2020	Safety of dapagliflozin in a broad population of patients with type 2 diabetes: Analyses from the DECLARE-TIMI 58 study.
11/2019	Dose-dependent glycometabolic effects of sotagliflozin on type 1 diabetes over 12 weeks: The inTandem4 trial.
1/2019	Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes.
9/2018	Sotagliflozin in Combination With Optimized Insulin Therapy in Adults With Type 1 Diabetes: The North American inTandem1 Study.
12/2017	Effects of Sotagliflozin Added to Insulin in Patients with Type 1 Diabetes.

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Darren K McGuire Research Topics

Disease

137	Type 2 Diabetes Mellitus (MODY) 10/2022 - 02/2005
76	Heart Failure 10/2022 - 07/2003
70	Cardiovascular Diseases (Cardiovascular Disease) 10/2022 - 07/2003
70	Myocardial Infarction 01/2022 - 12/2004
33	Diabetes Mellitus 11/2021 - 02/2004
29	Atherosclerosis 01/2017 - 11/2004
28	Stroke (Strokes) 01/2022 - 02/2008
21	Chronic Renal Insufficiency 10/2022 - 04/2006
19	Hypoglycemia (Reactive Hypoglycemia) 01/2022 - 04/2009
16	Coronary Artery Disease (Coronary Atherosclerosis) 01/2021 - 09/2004
14	Kidney Diseases (Kidney Disease) 08/2021 - 12/2014
14	Albuminuria 01/2021 - 04/2015
12	Acute Coronary Syndrome 06/2017 - 06/2002
10	Ischemic Stroke 01/2022 - 03/2016
10	Inflammation (Inflammations) 01/2020 - 09/2007
10	Coronary Disease (Coronary Heart Disease) 11/2018 - 02/2003
9	Hypertension (High Blood Pressure) 01/2022 - 11/2004
9	Hemorrhage 01/2021 - 10/2012
9	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 01/2021 - 12/2017
8	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2021 - 12/2017
8	Infections 01/2021 - 01/2009
8	Vascular Diseases (Vascular Disease) 11/2020 - 02/2007
8	Weight Loss (Weight Reduction) 10/2020 - 11/2016
8	Insulin Resistance 01/2020 - 06/2008
7	Unstable Angina 01/2022 - 10/2012
7	Body Weight (Weight, Body) 01/2022 - 08/2013
7	Obesity 01/2022 - 08/2007
6	Overweight 10/2021 - 09/2005
6	Atrial Fibrillation 01/2021 - 04/2017
6	Hyperglycemia 01/2020 - 06/2008
5	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 01/2020
5	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 01/2021 - 04/2006
5	Prediabetic State (Prediabetes) 01/2020 - 09/2012
5	Left Ventricular Dysfunction 01/2016 - 07/2003
5	ST Elevation Myocardial Infarction 02/2008 - 11/2004
4	Renal Insufficiency (Renal Failure) 08/2021 - 01/2018
4	Dyslipidemias (Dyslipidemia) 12/2020 - 01/2005
4	Pancreatitis 09/2019 - 10/2013
4	Weight Gain 09/2017 - 09/2012
4	Stable Angina 10/2015 - 05/2013
3	Cardiomyopathies (Cardiomyopathy) 09/2022 - 10/2019
3	Ketosis 09/2022 - 01/2021

Drug/Important Bio-Agent (IBA)

52	Glucose (Dextrose)FDA LinkGeneric 09/2022 - 11/2004
28	dapagliflozinIBA 10/2022 - 01/2018
23	Sodium-Glucose Transporter 2 InhibitorsIBA 10/2022 - 01/2017
22	Biomarkers (Surrogate Marker)IBA 11/2021 - 10/2005
21	Sodium-Glucose Transport ProteinsIBA 10/2022 - 12/2017
21	omega-Chloroacetophenone (Mace)IBA 01/2022 - 01/2018
19	CreatinineIBA 01/2022 - 04/2009
18	SodiumIBA 09/2022 - 10/2014
18	CalciumIBA 01/2017 - 09/2003
16	Insulin (Novolin)FDA Link 01/2021 - 11/2004
13	Hypoglycemic Agents (Hypoglycemics)IBA 01/2021 - 02/2004
12	empagliflozinIBA 10/2022 - 01/2016
12	Sitagliptin Phosphate (Januvia)FDA Link 01/2022 - 07/2015
11	Metformin (Glucophage)FDA LinkGeneric 01/2021 - 12/2007
11	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2021 - 05/2012
10	Natriuretic PeptidesIBA 09/2022 - 07/2003
10	LipidsIBA 01/2022 - 07/2005
10	(2S,3R,4R,5S,6R)- 2- (4- chloro- 3- (4- ethoxybenzyl)phenyl)- 6- (methylthio)tetrahydro- 2H- pyran- 3,4,5- triolIBA 01/2021 - 12/2017
10	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2021 - 02/2003
9	ertugliflozinIBA 05/2022 - 12/2018
9	saxagliptin FDA Link 11/2021 - 10/2013
9	Brain Natriuretic Peptide (Natrecor)FDA Link 11/2021 - 07/2003
9	AlbuminsIBA 01/2021 - 01/2014
9	Pharmaceutical PreparationsIBA 01/2021 - 06/2004
9	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2020 - 06/2002
8	pro-brain natriuretic peptide (1-76)IBA 09/2022 - 11/2005
8	LinagliptinIBA 09/2021 - 01/2018
8	C-Reactive ProteinIBA 01/2017 - 11/2004
8	Rosiglitazone (Avandia)FDA Link 03/2016 - 06/2007
7	Hemoglobins (Hemoglobin)IBA 01/2019 - 04/2011
6	insulin degludecIBA 01/2020 - 09/2016
6	Insulin Glargine (Lantus)FDA Link 01/2020 - 09/2016
6	LDL CholesterolIBA 01/2019 - 01/2017
6	Clopidogrel (Plavix)FDA Link 06/2017 - 02/2003
5	Troponin T (Troponin T1)IBA 11/2021 - 12/2010
5	Liraglutide FDA Link 12/2020 - 10/2017
5	Triglycerides (Triacylglycerol)IBA 01/2020 - 01/2005
5	Ranolazine FDA Link 10/2015 - 04/2009
4	PotassiumIBA 10/2022 - 11/2004
4	HDL CholesterolIBA 01/2022 - 04/2015
4	Glucagon-Like Peptide-1 Receptor AgonistsIBA 11/2021 - 01/2020
4	5-HT2C Serotonin ReceptorIBA 01/2019 - 01/2018
4	lorcaserinIBA 01/2019 - 01/2018
4	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2019 - 07/2015
4	Blood Glucose (Blood Sugar)IBA 01/2018 - 08/2013
4	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 09/2017 - 11/2005
4	Prasugrel Hydrochloride FDA Link 06/2017 - 10/2012
4	Proteins (Proteins, Gene)FDA Link 04/2013 - 05/2010
4	ThiazolidinedionesIBA 01/2008 - 01/2005
3	DiureticsIBA 10/2022 - 01/2020
3	CanagliflozinIBA 01/2022 - 01/2018
3	Sodium-Glucose Transporter 1IBA 01/2021 - 09/2018

Therapy/Procedure

45	Therapeutics 09/2022 - 06/2002
15	Glycemic Control 04/2021 - 02/2004
11	Percutaneous Coronary Intervention 01/2021 - 11/2004
10	Secondary Prevention 01/2021 - 06/2002
4	Surgical Amputation (Amputations) 01/2022 - 01/2020
4	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2022 - 06/2005